*Cold chain product


Adrim 50MG Inj

Atco Laboratories Limited


Rs. 1638.38/Pack

• Cold chain product

Lipodox is indicated for the treatment of metastatic carcinoma of the ovary in patients with disease that is refractory to both paclitaxel and platinum based chemotherapy regimens. Refractory disease is defined as disease that has progressed while on treatment or within 6 months of completing treatment.

Lipodox is indicated for the treatment of metastatic carcinoma of the ovary in patients with disease that is refractory to both paclitaxel and platinum based chemotherapy regimens. Refractory disease is defined as disease that has progressed while on treatment or within 6 months of completing treatment.
Experience with large cumulative doses of liposomal doxorubicin is very limited. Liposomal doxorubicin's cardiac risk and its risk compared to conventional doxorubicin formulations have not been adequately evaluated. At present, therefore, the warnings related to the use of conventional formulations of doxorubicin should be observed. It is recommended that all patients receiving liposomal doxorubicin routinely undergo frequent ECG monitoring. Transient ECG changes such as, T-wave flattening, S-T segment depression and benign arrhythmias are not considered mandatory indications for the suspension of liposomal doxorubicin therapy. However, reduction of the QRS complex is considered more indicative of cardiac toxicity. If this change occurs, the most definitive test for anthracycline myocardial injury i.e., endomyocardial biopsy, must be considered. More specific methods for the evaluation and monitoring of cardiac functions as compared to ECG are a measurement of left ventricular ejection fraction by echocardiography or preferably by multigated angiography (MUGA). These methods must be applied routinely before the initiation of liposomal doxorubicin therapy and repeated periodically during treatment. The evaluation of left ventricular function is considered to be mandatory before each additional administration of liposomal doxorubicin that exceeds a lifetime cumulative anthracycline dose of 450 mg/m?.
leucopenia, neutropenia, anemia, thrombocytopenia, palmar-plantar erythrodysesthesia
Experience with large cumulative doses of liposomal doxorubicin is very limited. Liposomal doxorubicin's cardiac risk and its risk compared to conventional doxorubicin formulations have not been adequately evaluated. At present, therefore, the warnings related to the use of conventional formulations of doxorubicin should be observed. It is recommended that all patients receiving liposomal doxorubicin routinely undergo frequent ECG monitoring. Transient ECG changes such as, T-wave flattening, S-T segment depression and benign arrhythmias are not considered mandatory indications for the suspension of liposomal doxorubicin therapy. However, reduction of the QRS complex is considered more indicative of cardiac toxicity. If this change occurs, the most definitive test for anthracycline myocardial injury i.e., endomyocardial biopsy, must be considered. More specific methods for the evaluation and monitoring of cardiac functions as compared to ECG are a measurement of left ventricular ejection fraction by echocardiography or preferably by multigated angiography (MUGA). These methods must be applied routinely before the initiation of liposomal doxorubicin therapy and repeated periodically during treatment. The evaluation of left ventricular function is considered to be mandatory before each additional administration of liposomal doxorubicin that exceeds a lifetime cumulative anthracycline dose of 450 mg/m?.
leucopenia, neutropenia, anemia, thrombocytopenia, palmar-plantar erythrodysesthesia

Adrim 50MG Inj Price in Pakistan - updated Apr 2026

Product Name
Product Price

Adrim 50MG Inj

Rs. 1,638.38

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